Why is studying reactive oxygen species important?
Reactive Oxygen Species (ROSs) are the main cause of oxidative stress and damage in cells, which is associated with the development of cancer, Alzheimer‘s disease, infections and Parkinson‘s disease, just to name a few. These free radicals have an unpaired electron, creating a highly reactive molecule that will try to obtain an additional electron from any source. In the cells and tissues of the human body this can result in major damage to lipids, proteins and DNA, ultimately affecting the function of cells, tissues and organs.
How can they be detected?
Direct detection of ROS is very difficult or impossible in solution at room temperature due to their very short half-life. Electron paramagnetic resonance (EPR) is the only method for the direct detection of paramagnetic species.
We’ve assembled a number of informative articles outlining the important research being done in this area, and the effective role EPR is playing. Read them all here!
As a leading provider of EPR instrumentation, Bruker’s application experts can answer your questions to see if EPR can further your research.